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Pharmaceutical and Service Companies

  • Accredo Therapeutics is a national network of pharmacies providing nursing and pharmacy services, as well as all four FDA-approved therapies to patients with Pulmonary Arterial Hypertension.
  • Actelion A subsidiary of a Swiss drug development company by the same name, which focuses on the endothelin. They are the developer of bosentan (Tracleer®), an oral dual endothelin receptor antagonist. Actelion has also in-licensed Ventavis® (iloprost) Inhalation Solution, from Schering AG, for the treatment of pulmonary arterial hypertension, an orphan indication, for the U.S. market.
  • Biogen Idec is developing aviptadil (vasoactive intestinal polypeptide) in collaboration with mondoBIOTECH. This investigational therapy is currently in Phase II clinical development for the treatment of PAH.
  • Caremark is a full-service provider for PAH therapies. The Caremark PAH Care Program focuses on the unique needs of individuals with PAH and carefully monitors patient care throughout the course of therapy. The company is staffed by a team of pharmacists, nurses, patient service representatives and reimbursement specialists.
    • Theracom site:Offers comprehensive reimbursement, clinical, and data collection and reporting solutions customized for the biotechnology and pharmaceutical manufacturer.
  • CuraScript is a provider of Remodulin®, Tracleer®, Revatio®, Letairis™ and epoprostenol. The company is a national distributor of specialty pharmaceuticals and related medical supplies to the alternate healthcare market.
  • Eli Lilly is the developer of Cialis (tadalafil). This oral medication is currently in Phase III trials for the treatment of PAH.
  • Encysive Pharmaceuticals is a biopharmaceutical company and the developers of sitaxsentan (Thelin®), which currently remains in Phase III clinical trials. Sitaxsentan is a small molecule that antagonizes the action of endothelin, a potent mediator of blood vessel constriction and growth of smooth muscle in vascular walls.
  • Gilead Sciences, formerly Myogen, is the maker of Letairis (ambrisentan). Gilead develops pharmaceuticals for a variety of life-threatening illnesses, including cardiovascular diseases. Gilead also markets and distributes Flolan through an agreement with GlaxoSmithKline.
  • GlaxoSmithKline Makers of Flolan®. This company was created through a merger of Glaxo Welcome and SmithKline Beecham.
  • Lung Rx is a separately managed affiliate of United Therapeutics focusing on several pharmaceutical products, including one early stage gene therapy solution for pulmonary hypertension (autologous cell-mediated eNOS).
  • Pfizer is the developer of Revatio® (sildenafil citrate), an oral PAH treatment approved by the FDA in June 2005.
  • Pharmaceutical Research and Manufacturers Association (PhRMA) is the leading association of research-based pharmaceutical and biotechnology companies.
    • Helpingpatients.org is their website dedicated to assisting patients and physicians determine eleigibility for available pharmaceutical support programs.
  • Teva Pharmaceuticals, a generic pharmaceutical manufacturer, markets approximately 380 products. The company manufactures Epoprostenol Sodium for Injection, along with a broad range of products in all major therapeutic categories, including cardiovascular, anti-infective, CNS, anti-inflammatory, oncolytic, antidiabetic, analgesic, dermatology, respiratory, and female healthcare.
  • United Therapeutics A niche pharmaceutical/disease management company dedicated to the development and marketing of innovative therapies for serious lung diseases, with a strong focus on PH.
    • Remodulin Therapy Assistance Program, a free service that provides non-medical support to patients on Remodulin® therapy.
    • PEER Network (Patients Exchanging Experiences with Remodulin) The goal of PEER is to provide an opportunity for people who are considering or who have recently started Remodulin to talk with an experienced Remodulin patient, called a PEER Mentor.

Other Companies Working in the Field:

  • Fairview Specialty Pharmacy provides personal medication management services for commonly prescribed pulmonary hypertension therapies including Letairis (Ambrisentan) and Revatio.
  • Medtronic manufactures pumps for use with Remodulin. Also manufactures a host of other products and therapies.
  • Pharmacare provides specialty pharmacy services for Tracleer.
  • Respironics provides information on sleep and respiratory issues.
  • Smiths Medical manufactures pumps for use with Flolan. Also manufactures a host of other products and therapies.

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